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KMID : 0391520160240010030
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Journal of the Korean Child Neurology Society
2016 Volume.24 No. 1 p.30 ~ p.32
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Viral Infection-related Isolated Hypoglossal Nerve Palsy in a 2 Year-old Girl
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Kim Tae-Ho
Kim Seung-Soo
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Abstract
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Isolated hypoglossal nerve palsy (HNP) is rare in children. Predominantly malignant
tumors are the most common cause of HNP, with trauma coming second. A 2-yearold
girl with acute onset dysarthria was referred to the pediatric neurology clinic.
She also had fever and left-sided tongue deviation upon protrusion. She had no
abnormal sign on physical, neurological, and otorhinolaryngological examination
other than left hypoglossal nerve palsy. She had no tongue fasciculation. Her brain
magnetic resonance imaging and magnetic resonance angiography were normal.
In a polymerase chain reaction test, enterovirus was positive in the stool and
adenovirus was positive in nasopharyngeal aspirate. We diagnosed viral infectionrelated
isolated HNP and prescribed prednisolone and acyclovir. Within a month,
the tongue deviation and dysarthria gradually improved. The first step for the
evaluation of isolated HNP should be investigation of the underlying malignancy.
However, serologic tests for viral infection are also needed.
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KEYWORD
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Hypoglossal nerve disease, Child, Enterovirus, Human adenovirus
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